HTA has always been leader in find new solutions. It has been in first instrument manufactures to introduce on liquid GC autosampler the capability to dilute/derivatize and to introduce the possibility to inject sample with Internal Standard.

Today, in consideration of labs needs to automate complex preparative method, we are proud to introduce, first between autosampler manufactures, the autosampler preparative station, that is able to help chemists and researchers in performing complex methodologies.

HT300APlus is based on HT300A, the GC liquid autosampler more reliable and affordable of the category, and on QUICKPREP, an easy-to-use but powerful software. It bundles the features of a standard liquid GC autosampler with the features of a mini versatile preparative station, at the cost not much higher than a stand-alone autosampler.

Operations

In "Autosampler" modality HT300APlus offers the same performances of HT300A. (Please visit HT300A page to learn about features and technical specification).

In "Preparative Station" modality HT300APlus is able to take care of a large number of preparative steps: users can write their favourite methods by selection of basic actions:

• Derivatisation: single and multiple (use of more solvents required), by solvent vials or by other sample vials on the tray. PH spiking is supported;
• Dilution: serial and parallel one's are supported;
• External events: total management of hand-shake signals; association with each functions and with each method steps is possible;
• Injections: total management of all relevant parameters (volumes, speed, delay). Partial Injections: use of different volume for drawing and for dispensing into the injector. Multiple Injections;
• Liquid displacing from vial to vial;
• Method: serial (preparative steps executed immediately before the injection, in order to uniform time from preparation to injection for all the samples) and parallel one's (preparative steps are performed for all the samples, then is performed injections in order to optimize time and reduce solvent use);
• Mixing by syringe;
• Solid Phase Extraction, by MEPS cartridge;
• Timer: to manage events and delay;
• Use in online modality (with direct injection into the GC, GC/MS or other supported analyzer) and offline modality (preparative operations without direct injection);
• Washing cycle: total management of liquid (solvents and samples), volumes, repetitions and selection of method steps.

In "Preparative Station" modality Personal Computer is required, in order to define method and to manage their execution. The software offers a multi-users rights system (different level of access for lab manager and operator) and the possibility to interact with external apps.

Application: MEPS (Micro Extraction by Packed Sorbent)

HTA is proud to announce the support to the MEPS by SGE

MEPS is the new development in the fields of sample preparation and sample handling. MEPS is the result of a collaboration between SGE and Mohamed Abdel-Rehim (AstraZeneca) and Lars G. Blomberg (University of Karlstead).

MEPS performs the same functions as SPE, the removal of interfering matrix components and the selective isolation and concentration of analytes. However MEPS increases the advantages of conventional SPE in the following ways:

• Ability to work with samples as small as 10μL or less;
• Significantly reduces the time needed to prepare and inject samples;
• Significantly reduces the volume of solvents needed.

MEPS technology is integrated in a syringe build up by two components: the barrel and the SPE cartridge (also known as BIN) mounted on a removable needle. The same cartridge could be used with an elevated number of samples: when it is exhausted can be easily changed by screwing off the needle.

To learn more about MEPS, visit SGE website.

To learn more about other solid phase extraction techniques supported by HTA, visit the following link