HT300L offers superior reliability and performances by its syringe sampling system. Within the standard configuration, we offer: Syringe (No low-cost / low-performance pressure based system), Full & Partial loop sampling techniques, Derivatisation and Dilution capability, and Bubble elimination functions.
By its flexibility and modularity configuration, fit quite all HPLC and LC/MS systems that are available on the market. Easy-to-use: programmed by the integrated keypad, by HT-COMSOFT-L, or by Clarity DataApex chromatography data system.
Within the standard configuration the autosampler is equipped with an automatic 6-way vertical injection-port valve. Although the rotating head design allows easy access to the injection valve for manual injections.
Direct syringe injection minimizes dead volume, reducing carry-over. By a short flow path (made up only by the syringe and the valve) is able to handle also the most aggressive solvents. Full and partial loop are performed both with very high accuracy values. In fact the accuracy of the sampled quantity is handled by the syringe (and not only by the loop, as per pressure based autosampler).
At the price of an entry-level autosampler, it can afford (already in the standard configuration) the derivation and the dilution of the sample. Furthermore, by a variable fill speed it allows for a wide range of sample viscosities with incredible performance (linearity: typical Area/Quantity value 0.999999).
Datasheet
Please refer to the brochure.
BIO Option
For handling biocompatible samples without buying expensive upgrade or dedicated autosamplers;
Large Volume Option
For injection sample up to 10ml and more. Based on the same HT300L platform, is provided with solvent and waste nozzle for unlimited solvent/waste capacity;
Plus Option
HT300LPlus, based on HT300L, bundles the features of a standard autosampler with the features of a mini versatile preparative station, at the cost not much higher than the standard autosampler.
In "Autosampler" modality HT300LPlus offers the same performances of HT300L. (Please visit HT300L page to learn about features and technical specification).
In "Preparative Station" modality HT300LPlus is able to take care of a large number of preparative steps: users can write their favourite methods by selection of basic actions:
- Derivatisation: single and multiple (use of more solvents required), by solvent vials or by other sample vials on the tray. PH spiking is supported;
- Dilution: serial and parallel one's are supported;
- External events: total management of hand-shake signals; association with each functions and with each method steps is possible;
- Injections: total management of all relevant parameters (volumes, speed, delay). Partial Injections: use of different volume for drawing and for dispensing into the injector. Multiple Injections;
- Liquid displacing from vial to vial;
- Method: serial (preparative steps executed immediately before the injection, in order to uniform time from preparation to injection for all the samples) and parallel one's (preparative steps are performed for all the samples, then is performed injections in order to optimize time and reduce solvent use);
- Mixing by syringe;
- Solid Phase Extraction, by MEPS cartridge;
- Timer: to manage events and delay;
- Use in online modality (with direct injection into the HPLC, LC/MS or other supported analyzer) and offline modality (preparative operations without direct injection);
- Washing cycle: total management of liquid (solvents and samples), volumes, repetitions and selection of method steps.
In "Preparative Station" modality Personal Computer is required, in order to define method and to manage their execution. The software offers a multi-users rights system (different level of access for lab manager and operator) and the possibility to interact with external apps.
HTA is proud to announce the support to the MEPS by SGE.
MEPS is the new development in the fields of sample preparation and sample handling. MEPS is the result of a collaboration between SGE and Mohamed Abdel-Rehim (AstraZeneca) and Lars G. Blomberg (University of Karlstead).
MEPS performs the same functions as SPE, the removal of interfering matrix components and the selective isolation and concentration of analytes. However MEPS increases the advantages of conventional SPE in the following ways:
- Ability to work with samples as small as 10μL or less;
- Significantly reduces the time needed to prepare and inject samples;
- Significantly reduces the volume of solvents needed.
MEPS technology is integrated in a syringe build up by two components: the barrel and the SPE cartridge (also known as BIN) mounted on a removable needle. The same cartridge could be used with an elevated number of samples: when it is exhausted can be easily changed by screwing off the needle.
To learn more about MEPS, visit SGE website.
To learn more about other solid phase extraction techniques supported by HTA, visit the following link
