Autosamplers and Sample Prep Workstations

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Sample Clean Up automation

Sample clean up is crucial for samples with complex matrices, such as biological fluids or food material. In fact, before proceeding with the injection into a LC or LC/MS system, the analytes of interest must be separated from the sample matrix.

This is a fundamental step to avoid that contaminants damage the analytical column or negatively affect the LC separation or the final detection. Sample clean up procedure can involve different steps:

  • sample derivatization with one or more buffers/reagents
  • sample heating at a set temperature for a fixed timing (to make some reactions – such as enzymatic digestion - occur
  • sample vortexing
  • sample clean up by SPE cartridges

Automation of sample clean up procedures assure higher reproducibility, increased productivity and even more sensitivity.

Discover HTA solutions for Sample Clean Up automation.

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